Claude Sonnet 4.5
Anthropic · moe · 150B parameters · 200,000 context
Parameters
150B
Context Window
195K tokens
Architecture
MoE
Best GPU
B200 NVL (pair)
Cheapest API
$15.00/M
Quality Score
86/100
Intelligence Brief
Claude Sonnet 4.5 is a 150B parameter Mixture-of-Experts (16 experts, 2 active) model from Anthropic, featuring Grouped Query Attention (GQA) with 64 layers and 10,240 hidden dimensions. With a 200,000 token context window, it supports tools, vision, structured output, code, math, multilingual, reasoning. On standardized benchmarks, it achieves MMLU 89, HumanEval 70, GSM8K 95. The most cost-effective API deployment is via anthropic at $15.00/M output tokens. For self-hosted inference, B200 NVL (pair) delivers optimal throughput at $9965/month.
Provider pricing
1 provider · canonical: anthropic| Provider | Input $/M | Output $/M ▲ | Notes |
|---|---|---|---|
| anthropiccanonical | $3.00 | $15.00 | cheapest input · cheapest output |
Prices update via the nightly pricing cron + admin approvals at /admin/ingest-queue. The leaderboard's Input/Output cells show the canonical rate above; this table shows the full spread.
Recent changes
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Picks: same family first, then same vendor within ±2× params, then top tag-overlap matches. Price shown is the cheapest Output $/M across providers — the row's page shows the canonical anchor.
Architecture Details
Memory Requirements
BF16 Weights
300.0 GB
FP8 Weights
150.0 GB
INT4 Weights
75.0 GB
GPU Compatibility Matrix
Claude Sonnet 4.5 is compatible with 19% of GPU configurations across 41 GPUs at 3 precision levels.
GPU Recommendations
BF16 · 1 GPU · tensorrt-llm
88/100
score
Throughput
280.0 tok/s
Latency (ITL)
3.6ms
Est. TTFT
1ms
Cost/Month
$9965
Cost/M Tokens
$13.54
BF16 · 4 GPUs · tensorrt-llm
85/100
score
Throughput
280.0 tok/s
Latency (ITL)
3.6ms
Est. TTFT
1ms
Cost/Month
$10211
Cost/M Tokens
$13.88
BF16 · 2 GPUs · tensorrt-llm
83/100
score
Throughput
280.0 tok/s
Latency (ITL)
3.6ms
Est. TTFT
1ms
Cost/Month
$8522
Cost/M Tokens
$11.58
Deployment Options
API Deployment
anthropic
$15.00/M
output tokens
Single GPU
B200 NVL (pair)
$9965/mo
Min VRAM: 150 GB
Multi-GPU
H200 SXM x4
280.0 tok/s
TP· $10211/mo
API Pricing Comparison
| Provider | Input $/M | Output $/M | Badges |
|---|---|---|---|
| anthropic | $3.00 | $15.00 | Cheapest |
Cost Analysis
| Provider | Input $/M | Output $/M | ~Monthly Cost |
|---|---|---|---|
| anthropicBest Value | $3.00 | $15.00 | $90 |
Cost per 1,000 Requests
Short (500 tok)
$4.50
via anthropic
Medium (2K tok)
$18.00
via anthropic
Long (8K tok)
$54.00
via anthropic
Performance Estimates
Throughput by GPU
VRAM Breakdown (B200 NVL (pair), BF16)
Quality Benchmarks
Capabilities
Features
Supported Frameworks
Supported Precisions
Where to Deploy Claude Sonnet 4.5
Similar Models
Claude 3 Opus
175B params · dense
Quality: 80
from $75.00/M
Claude 3.5 Sonnet
175B params · moe
Quality: 50
from $15.00/M
Claude Sonnet 4.6
180B params · moe
Quality: 86
from $15.00/M
Claude Opus 4
200B params · dense
Quality: 90
from $75.00/M
Claude 3 Sonnet
70B params · dense
Quality: 78
from $15.00/M
Frequently Asked Questions
How much VRAM does Claude Sonnet 4.5 need for inference?
Claude Sonnet 4.5 requires approximately 300.0 GB of VRAM at BF16 precision, 150.0 GB at FP8, or 75.0 GB at INT4 quantization. Additional VRAM is needed for KV-cache (204800 bytes per token) and activations (~4.00 GB).
What is the best GPU for Claude Sonnet 4.5?
The top recommended GPU for Claude Sonnet 4.5 is the B200 NVL (pair) using BF16 precision. It achieves approximately 280.0 tokens/sec at an estimated cost of $9965/month ($13.54/M tokens). Score: 88/100.
How much does Claude Sonnet 4.5 inference cost?
Claude Sonnet 4.5 API inference starts from $3.00/M input tokens and $15.00/M output tokens. Self-hosted inference costs depend on your GPU configuration — use our ROI calculator for a detailed breakdown.