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Updated minutes ago
ReleasedMarch 31, 2026Verified · huggingface.co
Mistral

Mistral Medium 3.5

Mistral AI · dense · 127.7B parameters · 262,144 context

Quality
50.0

Parameters

127.7B

Context Window

256K tokens

Architecture

Dense

Best GPU

B200 SXM

Cheapest API

$7.50/M

Intelligence Brief

Mistral Medium 3.5 is a 127.7B parameter DENSE model from Mistral AI, featuring Grouped Query Attention (GQA) with 88 layers and 12,288 hidden dimensions. With a 262,144 token context window, it supports vision, multilingual. The most cost-effective API deployment is via openrouter at $7.50/M output tokens. For self-hosted inference, B200 SXM delivers optimal throughput at $4261/month.

Provider pricing

1 provider · canonical: openrouter
Provider Input $/M Output $/M Notes
openroutercanonical$1.50$7.50cheapest input · cheapest output

Prices update via the nightly pricing cron + admin approvals at /admin/ingest-queue. The leaderboard's Input/Output cells show the canonical rate above; this table shows the full spread.

Recent changes

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Related models

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Picks: same family first, then same vendor within ±2× params, then top tag-overlap matches. Price shown is the cheapest Output $/M across providers — the row's page shows the canonical anchor.

Architecture Details

TypeDENSE
Total Parameters127.7B
Active Parameters127.7B
Layers88
Hidden Dimension12,288
Attention Heads96
KV Heads8
Head Dimension128
Vocab Size131,072

Memory Requirements

BF16 Weights

237.9 GB

FP8 Weights

118.9 GB

INT4 Weights

59.5 GB

KV-Cache per Token360448 bytes
Activation Estimate0.00 GB

GPU Compatibility Matrix

Mistral Medium 3.5 is compatible with 21% of GPU configurations across 41 GPUs at 3 precision levels.

BF16 (Full)
FP8 (Half)
INT4 (Quarter)
Blackwell(7 GPUs)
B200 NVL (pair)360GB
B300288GB
B100 SXM192GB
GB200 NVL72 (per GPU)192GB
Hopper(7 GPUs)
H100 NVL 94GB (per GPU pair)188GB
H200 SXM141GB
H2096GB
GH20096GB
Ada Lovelace(11 GPUs)
L40S48GB
L4048GB
RTX 6000 Ada48GB
L2048GB
Ampere(16 GPUs)
A100 80GB SXM80GB
A100 80GB PCIe80GB
A1664GB
RTX A600048GB
Legend:No fitVery tightTightModerateGoodExcellent

GPU Recommendations

B200 SXMoptimal

FP8 · 1 GPU · tensorrt-llm

100/100

score

Throughput

280.0 tok/s

Latency (ITL)

3.6ms

Est. TTFT

1ms

Cost/Month

$4261

Cost/M Tokens

$5.79

Use this config →
B100 SXMoptimal

FP8 · 1 GPU · tensorrt-llm

100/100

score

Throughput

280.0 tok/s

Latency (ITL)

3.6ms

Est. TTFT

1ms

Cost/Month

$4271

Cost/M Tokens

$5.80

Use this config →
GB200 NVL72 (per GPU)optimal

FP8 · 1 GPU · tensorrt-llm

100/100

score

Throughput

280.0 tok/s

Latency (ITL)

3.6ms

Est. TTFT

1ms

Cost/Month

$6169

Cost/M Tokens

$8.38

Use this config →

Deployment Options

API

API Deployment

openrouter

$7.50/M

output tokens

Self-Hosted

Single GPU

B200 SXM

$4261/mo

Min VRAM: 119 GB

Scale

Multi-GPU

H20 x2

280.0 tok/s

TP· $1879/mo

API Pricing Comparison

ProviderInput $/MOutput $/MBadges
openrouter$1.50$7.50
Cheapest

Cost Analysis

ProviderInput $/MOutput $/M~Monthly Cost
openrouterBest Value$1.50$7.50$45

Cost per 1,000 Requests

Short (500 tok)

$2.25

via openrouter

Medium (2K tok)

$9.00

via openrouter

Long (8K tok)

$27.00

via openrouter

Performance Estimates

Throughput by GPU

B200 SXM
280.0 tok/s
B100 SXM
280.0 tok/s
GB200 NVL72 (per GPU)
280.0 tok/s

VRAM Breakdown (B200 SXM, FP8)

Weights
Weights 127.7 GBKV-Cache 3.0 GBActivations 0.0 GBOverhead 6.4 GB

Precision Impact

bf16

255.4 GB

weights/GPU

fp8

127.7 GB

weights/GPU

~280.0 tok/s

int4

63.9 GB

weights/GPU

Capabilities

Features

Tool Use Vision Code Math Reasoning Multilingual Structured Output

Supported Frameworks

vllmsglang

Supported Precisions

BF16 (default)FP8INT4

Where to Deploy Mistral Medium 3.5

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Frequently Asked Questions

How much VRAM does Mistral Medium 3.5 need for inference?

Mistral Medium 3.5 requires approximately 237.9 GB of VRAM at BF16 precision, 118.9 GB at FP8, or 59.5 GB at INT4 quantization. Additional VRAM is needed for KV-cache (360448 bytes per token) and activations (~0.00 GB).

What is the best GPU for Mistral Medium 3.5?

The top recommended GPU for Mistral Medium 3.5 is the B200 SXM using FP8 precision. It achieves approximately 280.0 tokens/sec at an estimated cost of $4261/month ($5.79/M tokens). Score: 100/100.

How much does Mistral Medium 3.5 inference cost?

Mistral Medium 3.5 API inference starts from $1.50/M input tokens and $7.50/M output tokens. Self-hosted inference costs depend on your GPU configuration — use our ROI calculator for a detailed breakdown.